Jefferson County is located in the north-central part of Alabama and is the most populous county in the state. The county seat is Birmingham, the state's largest city.

Jefferson County is governed by a five-member county commission, which is elected from single-member districts. The county is also served by a sheriff, district attorney, probate judge, circuit court judge, and other county officials.

The county is home to several major universities, including the University of Alabama at Birmingham, Birmingham-Southern College, Miles College, and Samford University. It is also home to several major medical centers, including the University of Alabama at Birmingham Hospital, St. Vincent's Birmingham, and Children's of Alabama.

The county is served by several major highways, including Interstate 65, Interstate 59, and U.S. Route 11. It is also served by several major airports, including Birmingham-Shuttlesworth International Airport, Birmingham-Southern Regional Airport, and Bessemer Airport.

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