Cape Girardeau County is located in the southeastern corner of Missouri and is part of the Cape Girardeau–Jackson, MO–IL Metropolitan Statistical Area. The county seat is Jackson.

Cape Girardeau County is governed by a three-member County Commission. The County Commission is responsible for setting the budget, levying taxes, and making policy decisions. The County Commission is elected by the citizens of the county.

The county is served by the Cape Girardeau County Sheriff's Office, which is responsible for law enforcement and corrections.

The county is also served by the Cape Girardeau County Prosecuting Attorney's Office, which is responsible for prosecuting criminal cases.

The county is served by the Cape Girardeau County Health Department, which is responsible for public health and safety.

The county is served by the Cape Girardeau County Public Schools, which is responsible for providing public education.

For the most up-to-date and in-depth information, please check the public records links below.